In this study, a new method for manipulating energy flow in a Engraved Signatures 3D vector field is proposed.In this method, an azimuthally-polarized beam with a noncanonical vortex, the X-type vortex, is focused in a high-numerical aperture system.It is found that, instead of the invariance of the energy flow which is characteristic of the tradit
Effect of Lyophilization on Stability of PEG-Protein Conjugate: A Case Study with Peginterferon alfa-2b
Abstract The purpose of the present study was to develop stable lyophilized formulation of peginterferon alfa-2b which is acquiescent to the short lyophilization process.The present study evaluates the effect of buffering components and cryoprotectant(s) on depegylation of the peginterferon alfa-2b in combination with lyophilization process.Finally